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GSK1120212 ,Trametinib 871700-17-3
 
GSK1120212 ,Trametinib 871700-17-3
GSK1120212 (JTP-74057, trametinib) is a highly specific and potent MEK1 and MEK2 inhibitor with IC50 of 0.92 nM and 1.8 nM, respectively.
化学数据 点击下载GSK1120212 (Trametinib)SDF格式文件.SDF
分子量 615.39
化学式 C26H23FIN5O4
CAS号 871700-17-3, 871702-06-6 (sodium salt)

溶解性 (25°C)* DMSO 5 mg/mL
水 <1 mg/mL
乙醇 <1 mg/mL
稳定性 2年 -20°C粉状
2周 4°C溶于DMSO
6月-80°C溶于DMSO
别名 GSK212

化学名:N-(3-(3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

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