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DCC-2036 (Rebastinib) 1020172-07-9
DCC-2036 (Rebastinib) 1020172-07-9
DCC-2036是构像控制抑制剂,作用于ABL1和T315I ABL1时,IC50分别为0.8 nM 和 4 nM
化学数据
点击下载DCC-2036 (Rebastinib)SDF格式文件.SDF
分子量
553.59
化学式
C
30
H
28
FN
7
O
3
CAS号
1020172-07-9, 1020172-08-0 (2HCl), 1033893-29-6 (4-methylbenzenesulfonate)
溶解性 (25°C)
*
DMSO 111 mg/mL
水 <1 mg/mL
乙醇 16 mg/mL
稳定性
2年-20°C粉状
2周4°C溶于DMSO
6月-80°C溶于DMSO
别名
N/A
化学名:1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea
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