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Afatinib(BIBW2992) 439081-18-2
 
Afatinib(BIBW2992) 439081-18-2
BIBW2992不可逆地抑制EGFR/HER2，在体外作用于野生型EGFR ,L858R突变型EGFR, L858R/T790M 双突变型EGFR，及HER2时，IC50分别为0.5, 0.4, 10, 14 nM。
CBNumber: CB12470923
Chemical Name: Afatinib (BIBW 2992)
Molecular Formula: C24H25ClFN5O3
Formula Weight: 485.944
CAS No.: 439081-18-2
MOL File: Mol file


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