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WZ4002 1213269-23-8
WZ4002 1213269-23-8
WZ4002是新型选择性突变型EGFR激酶抑制剂,作用于EGFRL858R突变和EGFRL858R/T790M突变,IC50分别为2和8 nM
化学数据
点击下载WZ4002SDF格式文件.SDF
分子量
494.18
化学式
C
25
H
27
ClN
6
O
3
CAS号
1213269-23-8
溶解性 (25°C)
*
DMSO 13 mg/mL
水 <1 mg/mL
乙醇 <1 mg/mL
稳定性
2年 -20°C粉状
2周4°C溶于DMSO
6月-80°C溶于DMSO
别名
N/A
化学名:N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide
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