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AZD6244 (Selumetinib) ARRY-142886 606143-52-6
AZD6244 (Selumetinib) ARRY-142886 606143-52-6
AZD6244非常有效地抑制MEK1,IC50为14 nM
化学数据
点击下载AZD6244 (Selumetinib)SDF格式文件.SDF
分子量
457.68
化学式
C
17
H
15
BrClFN
4
O
3
CAS号
606143-52-6, 942275-12-9 (4-methylbenzenesulfonate)
溶解性 (25°C)
*
DMSO 92 mg/mL
水 <1 mg/mL
乙醇 <1 mg/mL
稳定性
2年 -20°C粉状
2周4°C溶于DMSO
6月-80°C溶于DMSO
别名
ARRY-142886
化学名:6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide
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