PaTrin-2,Lomeguatrib, 192441-08-0
Inhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 ¦ÌM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo. Enhances the antitumor activity of temozolomide (Cat. No. 2706) in both human melanoma and MCF-7 xenografts
Technical Data
M.Wt: 326.17
Formula: C₁₀H₈BrN₅OS
Solubility: Soluble to 100 mM in DMSO
Purity: >98 %
Storage: Store at +4¡ãC
CAS No: 192441-08-0
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.